Suicide mortality in the United States has risen steadily over the past fifteen years to become the tenth leading cause of death. Nonfatal self-harm behavior (the strongest risk factor for suicide) has increased concomitantly, particularly among adolescents. Efforts to turn this lethal tide are ongoing, although it is likely that only a sustained and multi-pronged public health response will reduce the toll. Healthcare settings such as emergency departments (EDs) are increasingly seen as playing an important role in this response, yet fundamental questions about the role of EDs in identifying and caring for potentially suicidal individuals remain unanswered. Which ED patients are at highest risk for suicide? Is hospitalization of those highest-risk patients an effective strategy for suicide prevention? What other adverse patient outcomes might we be missing by focusing solely on individuals’ suicide risk? Dr. Goldman-Mellor will explore these questions, and the implications of her findings for treatment models and suicide prevention programs in emergency care settings, drawing on her recent work using statewide emergency department data from California.