Public Health Seminar Series:

Epidemiology of HPV Related Cancers, the Unfolding Story by Margaret Madeleine, MPH, PhD

Friday, April 8, 2016 11:00AM - 12:00PM AIRB Room 2086 OCW Video Archive
Seminar Abstract

HPV has become a well-developed model for understanding viral carcinogenesis, and the interdisciplinary work that ensued allowed for the development of the HPV vaccine. The vaccine is nearly universally effective, and leads to an overwhelming and seemingly durable antibody response. Still, there has been a relatively slow rate of HPV vaccine in the U.S. and globally. This translates to continuing susceptibility to the six HPV-related cancers that could be averted. In my research, I seek to fill in the blanks in the HPV story, with a focus on immune response, including a newly emerging area of innate immunity of HPV. I will present my research on HPV-related cancers in immune competent and immunosuppressed populations, immunogenetics, and a proposed trial to assess the impact of the prophylactic vaccine to prevent recurrence of high-grade lesions. The HPV story has not yet been fully told, and my work is motivated by prevention of HPV-related cancers among those who are unvaccinated.

Speaker Biography - Margaret Madeleine, MPH, PhD

Margaret Madeleine, MPH, PhD
Margaret Madeleine, MPH, PhD Fred Hutchinson Cancer Research Center, Seattle, Washington
Dr. Margaret Madeleine is an Associate Member in the Program in Epidemiology at the Fred Hutchinson Cancer Research Center in Seattle, Washington. She also holds a position as an Assistant Research Professor in the Department of Epidemiology at the University of Washington, Seattle, where she earned her Ph.D. She earned her MPH degree at Yale School of Public Health. She has conducted research, collaborated and published extensively on cancer epidemiology. In 2011, she won the Team Science Award for Seattle HPV Research from the American Association for Cancer Research.

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