Neglected Tropical Diseases (NTDs) significantly challenge global health and perpetuate poverty in economically deprived areas of the world. Parasitic worms (helminths) infect over 1.5 billion humans, accounting for the greatest share of the overall NTD burden. My central ambition is to combine computational and molecular approaches to make discoveries that improve our understanding of the biology of these and our ability to treat the infections they cause. My graduate and postdoctoral work was focused on topics that include parasite genomics, drug target discovery, gene network inference, and host-parasite interactions. I will present my current research as a Data Science Fellow at Northwestern University, and outline a multi-faceted future research program with the goals of leveraging quantitative genetics to uncover novel mechanisms of parasite drug resistance, capturing parasite genetic diversity in the field, and extending genome editing technology to medically important parasites.
Speaker Biography - Mostafa Zamanian, Ph.D.
Mostafa Zamanian, Ph.D.
Data Science Fellow, Institute on Complex Systems, Department of Molecular Biosciences, Northwestern University
Dr. Zamanian is a Data Science Fellow at the Northwestern Institute on Complex Systems and the Department of Molecular Biosciences at Northwestern University. Dr. Zamanian's research is centered on Neglected Tropical Diseases (NTDs) that significantly challenge global human health, with a particular emphasis on parasitic worms that infect over 1.5 billion people worldwide. His current projects combine computational and molecular approaches to better understand parasite drug resistance, to capture parasite genetic diversity, and to extend genome editing technology to medically important parasites. Dr. Zamanian has been awarded funding from the Bill and Melinda Gates Foundation, and his work on parasite genomics and drug target discovery have appeared in leading journals. Dr. Zamanian received his Ph.D. (2011) in Neuroscience and B.S. in Biochemistry (2003) from Iowa State University, and trained as a postdoctoral fellow at McGill University.
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