Qualitative and quantitative studies have demonstrated that Arizona’s SB 1070 produces negative psychosocial health among Latinos in Phoenix, but there is no work examining how this type of stress is related to Latino immigrants and their children’s physiology. Numerous studies have related adversity from family stress, racism, and poverty to increased chronic disease risk in children and adults. The presentation will report on preliminary findings from a pilot study conducted in Phoenix, AZ examining the relationship between fear of deportation, BMI and salivary uric acid (sUA), a biomarker related to obesity and chronic disease risk, in a sample of Mexican-origin children (n = 65, 2 months-17 years, 49% female) and adults (n = 46, 20-58 years, 71% female). The pilot data are based on demographic, psychosocial and anthropometric data, and saliva samples (later assayed for sUA) from all participants. To explore patterns of sUA among children and their parents, we estimated structural equation models with multiple factors (age, BMI, gender, race, waist-to-hip ratio, and household fear of deportation) with levels of sUA for all individuals, in a two-group model to examine gender differences, and between families. Families were primarily low-income and mixed-status. Results suggest that BMI and developmental stage in relation to sUA levels are gender-specific, however, fear of deportation had in inverse effect on BMI and sUA. Future studies will examine what social and economic conditions of living with an undocumented family member affects healthy food access, diet quality and weight outcomes among Mexican-origin adults and children.